Prenatal maternal stress and atopic diseases in the child: a systematic review of observational human studies.

ABSTRACT:

Background

A growing number of studies suggest that maternal stress during pregnancy promotes atopic disorders in the offspring. This is the first systematic review to address prenatal maternal stress (PNMS) and the subsequent risk of atopy-related outcomes in the child.

Methods

The review was performed in accordance to the PRISMA criteria. We searched and selected studies in PubMed, Scopus, Embase and PsychINFO until November 2014.

Results

Sixteen (with 25 analyses) of 426 identified articles met the review criteria. Five main PNMS exposures (negative life events, anxiety/depression, bereavement, distress and job strain) and five main atopic outcomes (asthma, wheeze, atopic dermatitis, allergic rhinitis and IgE) were assessed across the studies. Overall, 21 of the 25

SUBMITTER: Andersson NW 

PROVIDER: S-EPMC5054838 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature