Biomechanical properties of infantile hemangiomas: clinical stage and effect of age.

ABSTRACT:

Background

Infantile hemangiomas (IHs) are benign vascular neoplasms with rapid capillary proliferation shortly after birth and slow involution with diminishing capillary proliferative activity, fibrosis, and fatty replacement over 7-10 years.

Methods

Hemangiomas and contralateral control sites in 88 subjects were measured using a suction device, 6-mm probe and 200 mbar negative pressure. Mechanical properties were assessed vs. controls and effects of body site, depth, clinical stage, histology diagnosis, and time.

Results

Biological elasticity, overall elasticity, net elasticity, total recovery, and elastic recovery were lower for IH vs. controls (P < 0.001). IH total deformation, elastic deformation, viscoelastic creep, and residual deformation were higher than cont

SUBMITTER: Visscher MO 

PROVIDER: S-EPMC5055468 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature