DNA-based culture-independent analysis detects the presence of group a streptococcus in throat samples from healthy adults in Japan.

ABSTRACT:

Background

Group A Streptococcus (GAS; Streptococcus pyogenes) causes a range of mild to severe infections in humans. It can also colonize healthy persons asymptomatically. Therefore, it is important to study GAS carriage in healthy populations, as carriage of it might lead to subsequent disease manifestation, clonal spread in the community, and/or diversification of the organism. Throat swab culture is the gold standard method for GAS detection. Advanced culture-independent methods provide rapid and efficient detection of microorganisms directly from clinical samples. We investigated the presence of GAS in throat swab samples from healthy adults in Japan using culture-dependent and culture-independent methods.

Results

Two throat swab samples were collected from 148 healthy

SUBMITTER: Kulkarni T 

PROVIDER: S-EPMC5057481 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature