Post-diagnosis adiposity and survival among breast cancer patients: influence of breast cancer subtype.

ABSTRACT:

Purpose

Adiposity has been linked with increased breast cancer risk and mortality. It is established that etiologic associations for adiposity vary by tumor subtype, but the influence of adiposity on subtype-specific survival is unknown.

Methods

Study participants were 1,109 invasive breast cancer participants in the population-based Carolina Breast Cancer Study, diagnosed between 1993 and 2001, and with tissue blocks available for immunohistochemical subtyping. General and central adiposities were assessed by body mass index (BMI) and waist-to-hip ratio (WHR), respectively, based on in-person measurements after diagnosis. Vital status as of 2011 was determined using the National Death Index (median follow-up = 13.5 years). Cox proportional hazards models were used to calcul

SUBMITTER: Sun X 

PROVIDER: S-EPMC5057532 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature