Evidence-Based interventions of Norovirus outbreaks in China.

ABSTRACT:

Background

In resource-limited settings where laboratory capacity is limited and response strategy is non-specific, delayed or inappropriate intervention against outbreaks of Norovirus (NoV) are common. Here we report interventions of two norovirus outbreaks, which highlight the importance of evidence-based modeling and assessment to identify infection sources and formulate effective response strategies.

Methods

Spatiotemporal scanning, mathematical and random walk modeling predicted the modes of transmission in the two incidents, which were supported by laboratory results and intervention outcomes.

Results

Simulation results indicated that contaminated water was 14 to 500 fold more infectious than infected individuals. Asymptomatic individuals were not effective tran

SUBMITTER: Chen T 

PROVIDER: S-EPMC5059926 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature