Dataset Information

Influenza C infections in Western Australia and Victoria from 2008 to 2014.

ABSTRACT:

Background

Influenza C is usually considered a minor cause of respiratory illness in humans with many infections being asymptomatic or clinically mild. Large outbreaks can occur periodically resulting in significant morbidity.

Objectives

This study aimed at analyzing the available influenza C clinical samples from two widely separated states of Australia, collected over a 7-year period and to compare them with influenza C viruses detected in other parts of the world in recent years.

Patients/methods

Between 2008 and 2014, 86 respiratory samples that were influenza C positive were collected from subjects with influenza-like illness living in the states of Victoria and Western Australia. A battery of other respiratory viruses were also tested for in these influenza C-positive samples. Virus isolation was attempted on all of these clinical samples, and gene sequencing was performed on all influenza C-positive cultures.

Results and conclusions

Detections of influenza C in respiratory samples were sporadic in most years studied, but higher rates of infection occurred in 2012 and 2014. Many of the patients with influenza C had coinfections with other respiratory pathogens. Phylogenetic analysis of the full-length hemagglutinin-esterase-fusion (HE) gene found that most of the viruses grouped in the C/Sao Paulo/378/82 clade with the remainder grouping in the C/Kanagawa/1/76 clade.

SUBMITTER: Jelley L

PROVIDER: S-EPMC5059950 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature

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Publications

Influenza C infections in Western Australia and Victoria from 2008 to 2014.

Jelley Lauren L Levy Avram A Deng Yi-Mo YM Spirason Natalie N Lang Jurissa J Buettner Iwona I Druce Julian J Blyth Chris C Effler Paul P Smith David D Barr Ian G IG

Influenza and other respiratory viruses 20160723 6

<h4>Background</h4>Influenza C is usually considered a minor cause of respiratory illness in humans with many infections being asymptomatic or clinically mild. Large outbreaks can occur periodically resulting in significant morbidity.<h4>Objectives</h4>This study aimed at analyzing the available influenza C clinical samples from two widely separated states of Australia, collected over a 7-year period and to compare them with influenza C viruses detected in other parts of the world in recent year ...[more]

PMID: 27373693

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Project description:BackgroundUsing government health datasets for secondary purposes is widespread; however, little is known on researchers' knowledge and reuse practices within Australia.ObjectivesTo explore researchers' knowledge and experience of governance processes, and their data reuse practices, when using Victorian government health datasets for research between 2008-2020.MethodA cross-sectional quantitative survey was conducted with authors who utilised selected Victorian, Australia, government health datasets for peer-reviewed research published between 2008-2020. Information was collected on researchers': data reuse practices; knowledge of government health information assets; perceptions of data trustworthiness for reuse; and demographic characteristics.ResultsWhen researchers used government health datasets, 45% linked their data, 45% found the data access process easy and 27% found it difficult. Government-curated datasets were significantly more difficult to access compared to other-agency curated datasets (p = 0.009). Many respondents received their data in less than six months (58%), in aggregated or de-identified form (76%). Most reported performing their own data validation checks (70%). To assist in data reuse, almost 71% of researchers utilised (or created) contextual documentation, 69% a data dictionary, and 62% limitations documentation. Almost 20% of respondents were not aware if data quality information existed for the dataset they had accessed. Researchers reported data was managed by custodians with rigorous confidentiality/privacy processes (94%) and good data quality processes (76%), yet half lacked knowledge of what these processes entailed. Many respondents (78%) were unaware if dataset owners had obtained consent from the dataset subjects for research applications of the data.ConclusionConfidentiality/privacy processes and quality control activities undertaken by data custodians were well-regarded. Many respondents included data linkage to additional government datasets in their research. Ease of data access was variable. Some documentation types were well provided and used, but improvement is required for the provision of data quality statements and limitations documentation. Provision of information on participants' informed consent in a dataset is required.

Dataset Information

Influenza C infections in Western Australia and Victoria from 2008 to 2014.

Background

Objectives

Patients/methods

Results and conclusions

Publications

Influenza C infections in Western Australia and Victoria from 2008 to 2014.

Similar Datasets

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