Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces.

ABSTRACT: All-aqueous emulsions exploit spontaneous liquid-liquid separation and due to their water-based nature are particular advantageous for the biocompatible storage and processing of biomacromolecules. However, the ultralow interfacial tensions characteristic of all-aqueous interfaces represent an inherent limitation to the use of thermally adsorbed particles to achieve emulsion stability. Here, we use protein nanofibrils to generate colloidosome-like two-dimensional crosslinked networks of nanostructures templated by all-aqueous emulsions, which we term fibrillosomes. We show that this approach not only allows us to operate below the thermal limit at ultra-low surface tensions but also yields structures that are stable even in the complete absence of an interface. Moreover, we show that the g

SUBMITTER: Song Y 

PROVIDER: S-EPMC5062572 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature