A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.

ABSTRACT: The African Diaspora in the Western Hemisphere represents one of the largest forced migrations in history and had a profound impact on genetic diversity in modern populations. To date, the fine-scale population structure of descendants of the African Diaspora remains largely uncharacterized. Here we present genetic variation from deeply sequenced genomes of 642 individuals from North and South American, Caribbean and West African populations, substantially increasing the lexicon of human genomic variation and suggesting much variation remains to be discovered in African-admixed populations in the Americas. We summarize genetic variation in these populations, quantifying the postcolonial sex-biased European gene flow across multiple regions. Moreover, we refine estimates on the burden of de

SUBMITTER: Mathias RA 

PROVIDER: S-EPMC5062574 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature