Non-specific immunological effects of selected routine childhood immunisations: systematic review.

ABSTRACT:

Objective

 To identify and characterise non-specific immunological effects after routine childhood vaccines against BCG, measles, diphtheria, pertussis, and tetanus.

Design

 Systematic review of randomised controlled trials, cohort studies, and case-control studies.

Data sources

 Embase, PubMed, Cochrane library, and Trip searched between 1947 and January 2014. Publications submitted by a panel of experts in the specialty were also included.

Eligibility criteria for selecting studies

 All human studies reporting non-specific immunological effects after vaccination with standard childhood immunisations. Studies using recombinant vaccines, no vaccine at all, or reporting only vaccine specific outcomes were excluded. The primary aim was to systematically identify,

SUBMITTER: Kandasamy R 

PROVIDER: S-EPMC5063033 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature