Ontology highlight
ABSTRACT:
SUBMITTER: Cavalli RC
PROVIDER: S-EPMC5063315 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
PloS one 20161013 10
Decidual NK (dNK) cells, a distinct type of NK cell, are thought to regulate uterine spiral artery remodeling, a process that allows for increased blood delivery to the fetal-placental unit. Impairment of uterine spiral artery remodeling is associated with decreased placental perfusion, increased uterine artery resistance, and obstetric complications such as preeclampsia and intrauterine growth restriction. Ex vivo manipulation of human peripheral blood NK (pNK) cells by a combination of hypoxia ...[more]