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Data on the potential impact of food supplements on the growth of mouse embryonic stem cells.


ABSTRACT: The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine and Tauroursodeoxycholic acid (TUDCA). Cell number and viability were monitored following treatment with increased concentrations of each drug in pluripotent culture conditions.

SUBMITTER: Correia M 

PROVIDER: S-EPMC5063814 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Data on the potential impact of food supplements on the growth of mouse embryonic stem cells.

Correia Marcelo M   Sousa Maria I MI   Rodrigues Ana S AS   Perestrelo Tânia T   Pereira Sandro L SL   Ribeiro Marcelo F MF   Ramalho-Santos João J  

Data in brief 20160404


The use of new compounds as dietary supplements is increasing, but little is known in terms of possible consequences of their use. Pluripotent stem cells are a promising research tool for citotoxicological research for evaluation of proliferation, cell death, pluripotency and differentiation. Using the mouse embryonic stem cell (mESC) model, we present data on three different compounds that have been proposed as new potential supplements for co-adjuvant disease treatments: kaempferol, berberine  ...[more]

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