Neurally adjusted ventilatory assist in patients with acute respiratory failure: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Patient-ventilator asynchrony is a common problem in mechanically ventilated patients with acute respiratory failure. It is assumed that asynchronies worsen lung function and prolong the duration of mechanical ventilation (MV). Neurally Adjusted Ventilatory Assist (NAVA) is a novel approach to MV based on neural respiratory center output that is able to trigger, cycle, and regulate the ventilatory cycle. We hypothesized that the use of NAVA compared to conventional lung-protective MV will result in a reduction of the duration of MV. It is further hypothesized that NAVA compared to conventional lung-protective MV will result in a decrease in the length of ICU and hospital stay, and mortality.

Methods/design

This is a prospective, multicenter, randomized controlled

SUBMITTER: Villar J 

PROVIDER: S-EPMC5064782 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature