Anxiety is related to indices of cortical maturation in typically developing children and adolescents.

ABSTRACT: Anxiety is a risk factor for many adverse neuropsychiatric and socioeconomic outcomes, and has been linked to functional and structural changes in the ventromedial prefrontal cortex (VMPFC). However, the nature of these differences, as well as how they develop in children and adolescents, remains poorly understood. More effective interventions to minimize the negative consequences of anxiety require better understanding of its neurobiology in children. Recent research suggests that structural imaging studies may benefit from clearly delineating between cortical surface area and thickness when examining these associations, as these distinct cortical phenotypes are influenced by different cellular mechanisms and genetic factors. The present study examined relationships between cortical surfa

SUBMITTER: Newman E 

PROVIDER: S-EPMC5064818 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature