Phenotypic and molecular characteristics associated with various domains of quality of life in oncology patients and their family caregivers.

ABSTRACT:

Purpose

Not all oncology patients and their family caregivers (FCs) experience the same quality of life (QOL). The purposes of this study were to identify latent classes of oncology patients (n = 168) and their FCs (n = 85) with distinct physical, psychological, social, and spiritual well-being trajectories from prior to through 4 months after the completion of radiation therapy and to evaluate for demographic, clinical, and genetic characteristics that distinguished between these latent classes.

Methods

Using growth mixture modeling, two latent classes were found for three (i.e., physical, psychological, and social well-being) of the four QOL domains evaluated.

Results

Across these three domains, the largest percentage of participants reported relatively high well-be

SUBMITTER: Alexander KE 

PROVIDER: S-EPMC5065744 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature