Invasive Trichosporon Infection: a Systematic Review on a Re-emerging Fungal Pathogen.

ABSTRACT: Objectives: This review aimed to better depict the clinical features and address the issue of therapeutic management of Trichosporon deep-seated infections. Methods: We comprehensively reviewed the cases of invasive Trichosporon infection reported in the literature from 1994 (date of taxonomic modification) to 2015. Data from antifungal susceptibility testing (AST) studies were also analyzed. Results: Two hundred and three cases were retained and split into four groups: homeopathy (n = 79), other immunodeficiency conditions (n = 41), miscellaneous (n = 58) and newborns (n = 25). Trichosporon asahii was the main causative species (46.7%) and may exhibit cross-resistance to different antifungal classes. The unfavorable out

SUBMITTER: de Almeida Junior JN 

PROVIDER: S-EPMC5065970 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature