Association of Left Atrial Enlargement with Cortical Infarction in Subjects with Patent Foramen Ovale.

ABSTRACT:

Background and purpose

Left atrial dysfunction has been reported in patients with patent foramen ovale (PFO). Here we investigated the role of left atrial dysfunction in the development of embolic stroke in patients with PFO.

Methods

We identified consecutive patients with embolic stroke of undetermined sources except for PFO (PFO+ESUS). Healthy subjects with PFO served as controls (PFO+control). A stratified analysis by 10-year age group and an age- and sex- matching analysis were performed to compare echocardiographic markers between groups. In the PFO+ESUS group, infarct patterns of PFO-related stroke were determined (cortical vs. cortico-subcortical) and analyzed in correlation with left atrial function parameters.

Results

A total of 118 patients and 231 controls

SUBMITTER: Lee MJ 

PROVIDER: S-EPMC5066430 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature