Association between Aortic Atheroma and Cerebral Small Vessel Disease in Patients with Ischemic Stroke.

ABSTRACT:

Background and purpose

Cerebral small vessel disease (SVDs) are related with large artery atherosclerosis. However, the association between aortic atheroma (AA) and cerebral small vessel disease has rarely been reported. This study evaluated the relationship between presence and burden of AAs and those of SVDs in patients with acute ischemic stroke.

Methods

We included 737 consecutive patients who underwent transesophageal echocardiography (TEE) and brain magnetic resonance imaging (MRI) for evaluation of acute stroke. AA subtypes were classified as complex aortic plaque (CAP) and simple aortic plaque (SAP). Presence and burden of SVDs including cerebral microbleeds (CMBs), white matter hyperintensities (WMHs), perivascular spaces (PVSs), asymptomatic lacunar infarctions (AL

SUBMITTER: Song TJ 

PROVIDER: S-EPMC5066433 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature