Sex differences in the association between stressor-evoked interleukin-6 reactivity and C-reactive protein.

ABSTRACT: Individuals differ consistently in the magnitude of their inflammatory responses to acute stressors, with females often showing larger responses than males. While the clinical significance of these individual differences remains unclear, it may be that greater inflammatory responses relate to increased systemic inflammation and thereby risk for chronic inflammatory disease. Here, we examined whether acute stressor-evoked interleukin (IL)-6 responses associate with resting levels of C-reactive protein (CRP), a marker of systemic inflammation, and whether this association differs by sex. Subjects were 57 healthy midlife adults (30-51years; 33% female; 68% white). Blood was drawn before and 30-min after two mental stress tasks: a multisource interference task and a Stroop color word task. Hie

SUBMITTER: Lockwood KG 

PROVIDER: S-EPMC5067187 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature