Omega-3 Fatty Acids and Cardiovascular Disease: Are There Benefits?

ABSTRACT:

Opinion statement

Early secondary prevention trials of fish and omega-3 polyunsaturated fatty acid (PUFA) capsules reported beneficial effects on cardiovascular disease (CVD) outcomes, including all-cause mortality and sudden cardiac death. These clinical findings, as well as observational and experimental data, demonstrated that omega-3 PUFAs reduced the risk of coronary outcomes and overall mortality and were the basis for recommendations made in the early 2000s to increase omega-3 PUFA intake. In the last 6 years, however, results from both primary and secondary prevention trials have generally failed to show a beneficial effect of omega-3 PUFA supplementation, bringing current recommendations into question. Several possible reasons for these null findings have been proposed, in

SUBMITTER: Bowen KJ 

PROVIDER: S-EPMC5067287 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature