Clinical inertia with regard to intensifying therapy in people with type 2 diabetes treated with basal insulin.

ABSTRACT:

Aim

To investigate whether clinical inertia, the failure to intensify treatment regimens when required, exists in people with type 2 diabetes treated with basal insulin.

Methods

This was a retrospective cohort study involving patients with type 2 diabetes in the UK Clinical Practice Research Datalink database between January 2004 and December 2011, with follow-up until December 2013.

Results

A total of 11 696 patients were included in the analysis. Among all patients, 36.5% had their treatment intensified during the study period; of these, the treatment of 50.0, 42.5 and 7.4% was intensified with bolus or premix insulin or glucagon-like peptide-1 receptor agonists, respectively. The median time from initiation of basal insulin to treatment intensification was 4.3 year

SUBMITTER: Khunti K 

PROVIDER: S-EPMC5067688 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature