Influence of Lung Function and Sleep-disordered Breathing on All-Cause Mortality. A Community-based Study.

ABSTRACT:

Rationale

Whether sleep-disordered breathing (SDB) severity and diminished lung function act synergistically to heighten the risk of adverse health outcomes remains a topic of significant debate.

Objectives

The current study sought to determine whether the association between lower lung function and mortality would be stronger in those with increasing severity of SDB in a community-based cohort of middle-aged and older adults.

Methods

Full montage home sleep testing and spirometry data were analyzed on 6,173 participants of the Sleep Heart Health Study. Proportional hazards models were used to calculate risk for all-cause mortality, with FEV₁ and apnea-hypopnea index (AHI) as the primary exposure indicators along with several potential confounders.

Measu

SUBMITTER: Putcha N 

PROVIDER: S-EPMC5067819 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature