Heritability of Lower Urinary Tract Symptoms in Men: A Twin Study.

ABSTRACT:

Purpose

Symptoms of urinary irritation, urgency, frequency and obstruction, known as lower urinary tract symptoms, are common in urological practice. However, little is known about the etiology or pathogenesis of lower urinary tract symptoms, especially the relative contributions of genetic and environmental factors to the development of these symptoms. We used a classic twin study design to examine the relative contributions of genetic and environmental factors to the occurrence of lower urinary tract symptoms in middle-aged men.

Materials and methods

Twins were members of the Vietnam Era Twin Registry. We used a mail survey to collect data on lower urinary tract symptoms using the I-PSS (International Prostate Symptom Score) instrument. Twin correlations and biometric mode

SUBMITTER: Afari N 

PROVIDER: S-EPMC5069121 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature