Prevalence and Predictors of Gastroesophageal Reflux Complications in Community Subjects.

ABSTRACT:

Background

Predictors of erosive esophagitis (EE) and Barrett's esophagus (BE) and the influence of number of risk factors in the community are not well defined.

Methods

Rates of BE and EE among community residents identified in a randomized screening trial were defined. The risk of EE and BE associated with single and multiple risk factors (gender, age, GERD, Caucasian ethnicity, ever tobacco use, excess alcohol use, family history of BE or EAC, and central obesity) was analyzed.

Results

Sixty-eight (33 %) of 205 subjects had EE and/or BE. BE prevalence was 7.8 % with dysplasia present in 1.5 %. Rates were comparable between subjects with and without GERD. Male sex and central obesity were independent risk factors. The odds of EE or BE were 3.7 times higher in subjec

SUBMITTER: Crews NR 

PROVIDER: S-EPMC5069175 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature