Two Behavioral Interventions for Patients with Major Depression and Severe COPD.

ABSTRACT:

Objective

Personalized Intervention for Depressed Patients with COPD (PID-C), a treatment mobilizing patients to participate in their care, was found more effective than usual care. To further improve its efficacy, we developed a Problem Solving-Adherence (PSA) intervention integrating problem solving into adherence enhancement procedures. We tested the hypothesis that PSA is more effective than PID-C in reducing depressive symptoms. Exploratory analyses sought to identify patients with distinct depressive symptom trajectories and compare their clinical profiles.

Design

Randomized controlled trial.

Setting

Acute inpatient rehabilitation and community.

Participants

A total of 101 diagnosed with chronic obstructive pulmonary disease (COPD) and major depression af

SUBMITTER: Alexopoulos GS 

PROVIDER: S-EPMC5069195 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature