The rate of brain death and organ donation in patients resuscitated from cardiac arrest: a systematic review and meta-analysis.

ABSTRACT:

Background

The occurrence of brain death in patients with hypoxic-ischaemic brain injury after resuscitation from cardiac arrest creates opportunities for organ donation. However, its prevalence is currently unknown.

Methods

Systematic review. MEDLINE via PubMed, ISI Web of Science and the Cochrane Database of Systematic Reviews were searched for eligible studies (2002-2016). The prevalence of brain death in adult patients resuscitated from cardiac arrest and the rate of organ donation among brain dead patients were summarised using a random effect model with double-arcsine transformation. The quality of evidence (QOE) was evaluated according to the GRADE guidelines.

Results

26 studies [16 on conventional cardiopulmonary resuscitation (c-CPR), 10 on extracorporeal CPR

SUBMITTER: Sandroni C 

PROVIDER: S-EPMC5069310 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature