A task-based assessment of parental occupational exposure to organic solvents and other compounds and the risk of childhood leukemia in California.

ABSTRACT:

Purpose

Data on parental occupational exposures and risk of childhood leukemia lack specificity. Using 19 task-based job modules, we examined the relationship between occupational exposure to organic solvents and other compounds and the risk of leukemia in children.

Methods

Latino (48%) and non-Latino (52%) children with acute lymphoblastic leukemia (ALL; n=670), acute myeloid leukemia (AML; n=104), and controls (n=1021) were enrolled in a study in California (2000-2008). Logistic regression models were used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs), adjusted for socio-demographic factors.

Results

Among children with non-Latino fathers, none of the exposures evaluated were associated with risks of ALL and AML. In contrast, exposure to any or

SUBMITTER: Metayer C 

PROVIDER: S-EPMC5071154 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature