SPRYSEC Effectors: A Versatile Protein-Binding Platform to Disrupt Plant Innate Immunity.

ABSTRACT: Persistent infections by sedentary plant-parasitic nematodes are a major threat to important food crops all over the world. These roundworms manipulate host plant cell morphology and physiology to establish sophisticated feeding structures. Key modifications to plant cells during their transition into feeding structures are largely attributed to the activity of effectors secreted by the nematodes. The SPRYSEC effectors were initially identified in the potato cyst nematodes Globodera rostochiensis and G. pallida, and are characterized by a single SPRY domain, a non-catalytic domain present in modular proteins with different functions. The SPRY domain is wide-spread among eukaryotes and thought to be involved in mediating protein-protein interactions. Thus far, the SPRY domain

SUBMITTER: Diaz-Granados A 

PROVIDER: S-EPMC5071358 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature