Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata.

ABSTRACT: Two new phenylpropanoid glycosides named cuneataside E (1) and cuneataside F (2), were isolated from the aerial parts of Lespedeza cuneata (Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D NMR). In in vitro bioassays at 10 μmol/L, compound 1 showed moderate hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced toxicity in HeG2 cells.

SUBMITTER: Zhang C 

PROVIDER: S-EPMC5071639 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature