Magnetophoretic transistors in a tri-axial magnetic field.

ABSTRACT: The ability to direct and sort individual biological and non-biological particles into spatially addressable locations is fundamentally important to the emerging field of single cell biology. Towards this goal, we demonstrate a new class of magnetophoretic transistors, which can switch single magnetically labeled cells and magnetic beads between different paths in a microfluidic chamber. Compared with prior work on magnetophoretic transistors driven by a two-dimensional in-plane rotating field, the addition of a vertical magnetic field bias provides significant advantages in preventing the formation of particle clumps and in better replicating the operating principles of circuits in general. However, the three-dimensional driving field requires a complete redesign of the magnetic track geo

SUBMITTER: Abedini-Nassab R 

PROVIDER: S-EPMC5072173 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature