The Relationship between Parkinson Disease and Brain Tumor: A Meta-Analysis.

ABSTRACT:

Objective

Epidemiological studies have investigated the association between Parkinson disease (PD) occurrence and the risk of brain tumors, while the results remain controversial. We performed a meta-analysis to clarify the exact relationship between PD and brain tumors.

Methods

A systematic literature search was conducted using PubMed, Embase, ScienceDirect and CBM (China Biology Medicine Disc) before February 2016. Eligible studies were those that reported risk estimates of brain tumors among patients with PD or vice versa. A random-effects model was used to calculate the pooled odds ratio (OR) of the outcomes. Subgroup analyses and sensitivity analysis were conducted to explore the potential sources of heterogeneity.

Results

In total, eight studies involving 329,27

SUBMITTER: Ye R 

PROVIDER: S-EPMC5072611 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature