Associations between excessive adiposity and seroprevalence of herpes simplex virus type 1 and type 2 among US adults: a population-based age-period-cohort analysis.

ABSTRACT:

Objectives

Evidence on the association between herpes simplex virus (HSV) and excessive adiposity, such as obesity (body mass index ≥30 kg/m²) and abdominal obesity (waist circumference (WC) >102 or 88 cm), has been inconsistent. We sought to examine whether age-period-cohort (APC) effects could explain for the observed heterogeneities.

Design

Population-based cross-sectional study.

Participants

Adults aged 20-49 years with available serological data in the National Health and Nutrition Examination Survey (NHANES) in 1999-2012.

Exposure measures

Obesity and abdominal obesity.

Results

In men, excessive adiposity was generally not associated with HSV1 or HSV2 (all p>0.05); however, there were positive correlations between HSV seroprevalence and

SUBMITTER: Liu SH 

PROVIDER: S-EPMC5073520 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature