Fructose intake and risk of gout and hyperuricemia: a systematic review and meta-analysis of prospective cohort studies.

ABSTRACT:

Background

The prevalence of hyperuricemia and gout has increased in recent decades. The role of dietary fructose in the development of these conditions remains unclear.

Objective

To conduct a systematic review and meta-analysis of prospective cohort studies investigating the association fructose consumption with incident gout and hyperuricemia.

Design

MEDLINE, EMBASE and the Cochrane Library were searched (through September 2015). We included prospective cohort studies that assessed fructose consumption and incident gout or hyperuricemia. 2 independent reviewers extracted relevant data and assessed study quality using the Newcastle-Ottawa Scale. We pooled natural-log transformed risk ratios (RRs) using the generic inverse variance method. Interstudy heterogeneity was

SUBMITTER: Jamnik J 

PROVIDER: S-EPMC5073537 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature