Spontaneous preterm birth and single nucleotide gene polymorphisms: a recent update.

ABSTRACT:

Background

Preterm birth (PTB), birth at <37 weeks of gestation, is a significant global public health problem. World-wide, about 15 million babies are born preterm each year resulting in more than a million deaths of children. Preterm neonates are more prone to problems and need intensive care hospitalization. Health issues may persist through early adulthood and even be carried on to the next generation. Majority (70 %) of PTBs are spontaneous with about a half without any apparent cause and the other half associated with a number of risk factors. Genetic factors are one of the significant risks for PTB. The focus of this review is on single nucleotide gene polymorphisms (SNPs) that are reported to be associated with PTB.

Results

A comprehensive evaluation of studies on SN

SUBMITTER: Sheikh IA 

PROVIDER: S-EPMC5073925 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature