More comprehensive forensic genetic marker analyses for accurate human remains identification using massively parallel DNA sequencing.

ABSTRACT:

Background

Although the primary objective of forensic DNA analyses of unidentified human remains is positive identification, cases involving historical or archaeological skeletal remains often lack reference samples for comparison. Massively parallel sequencing (MPS) offers an opportunity to provide biometric data in such cases, and these cases provide valuable data on the feasibility of applying MPS for characterization of modern forensic casework samples. In this study, MPS was used to characterize 140-year-old human skeletal remains discovered at a historical site in Deadwood, South Dakota, United States. The remains were in an unmarked grave and there were no records or other metadata available regarding the identity of the individual. Due to the high throughput of MPS, a varie

SUBMITTER: Ambers AD 

PROVIDER: S-EPMC5073988 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature