Kidney function and sudden cardiac death in the community: The Atherosclerosis Risk in Communities (ARIC) Study.

ABSTRACT:

Background

Individuals with chronic kidney disease, particularly those requiring dialysis, are at high risk of sudden cardiac death (SCD). However, comprehensive data for the full spectrum of kidney function and SCD risk in the community are sparse. Furthermore, newly developed equations for estimated glomerular filtration rate (eGFR) and novel filtration markers might add further insight to the role of kidney function in SCD.

Methods

We investigated the associations of baseline eGFRs using serum creatinine, cystatin C, or both (eGFRcr, eGFRcys, and eGFRcr-cys); cystatin C itself; and β2-microglobulin (B2M) with SCD (205 cases through 2001) among 13,070 black and white ARIC participants at baseline during 1990-1992 using Cox regression models accounting for potential confoun

SUBMITTER: Suzuki T 

PROVIDER: S-EPMC5074685 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature