Respiratory syncytial virus immunoprophylaxis in high-risk infants and development of childhood asthma.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) lower respiratory tract infection is implicated in asthma development. RSV immunoprophylaxis during infancy is efficacious in preventing RSV-related hospitalizations and has been associated with decreased wheezing in the first years of life.

Objective

We investigated whether greater adherence to immunoprophylaxis in infants at high risk for severe RSV would be associated with decreased childhood asthma.

Methods

We conducted a retrospective cohort investigation including children born from 1996-2003 who were enrolled in Kaiser Permanente Northern California or Tennessee Medicaid and eligible to receive RSV immunoprophylaxis. Asthma was defined at 4.5 to 6 years of age by using asthma-specific health care visits and medicatio

SUBMITTER: Carroll KN 

PROVIDER: S-EPMC5074917 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature