IncHI2 Plasmids Are the Key Vectors Responsible for oqxAB Transmission among Salmonella Species.

ABSTRACT: This study reported and analyzed the complete sequences of two oqxAB-bearing IncHI2 plasmids harbored by a clinical Salmonella enterica serovar Typhimurium strain and an S Indiana strain of animal origin, respectively. In particular, pA3T recovered from S Indiana comprised the resistance determinants oqxAB, aac(6')Ib-cr, fosA3, and bla_CTX-M-14 Further genetic screening of 63 oqxAB-positive Salmonella isolates revealed that the majority carried IncHI2 plasmids, confirming that such plasmids play a pivotal role in dissemination of oqxAB in Salmonella spp.

SUBMITTER: Wong MH 

PROVIDER: S-EPMC5075106 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature