Divergent relationship of circulating CTRP3 levels between obesity and gender: a cross-sectional study.

ABSTRACT: C1q TNF Related Protein 3 (CTRP3) is a novel adipose tissue derived secreted factor, or adipokine, which has been linked to a number of beneficial biological effects on metabolism, inflammation, and survival signaling in a variety of tissues. However, very little is known about CTRP3 in regards to human health. The purpose of this project was to examine circulating CTRP3 levels in a clinical population, patients with symptoms requiring heart catheterization in order to identify the presence of obstructive coronary artery disease (CAD). It was hypothesized that serum CTRP3 levels would be decreased in the presence of CAD.

Methods

Body mass index (BMI), diabetes status, and plasma samples were collected from 100 patients who were >30 years of age and presented at the East Tennessee St

SUBMITTER: Wagner RM 

PROVIDER: S-EPMC5075694 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature