Hormone therapy use and physical quality of life in postmenopausal women with multiple sclerosis.

ABSTRACT:

Objective

To determine the association between hormone therapy (HT) and physical quality of life (QOL) in postmenopausal women with multiple sclerosis (MS).

Methods

We included female participants from the prospective Nurses' Health Study, with a diagnosis of definite or probable MS, who had completed a physical functioning assessment (PF10; subscale of the 36-Item Short-Form Health Survey QOL survey) at a time point between 3 and 10 years after their final menstrual period (early postmenopause). We assessed the association between HT use at this time point (never vs at least 12 months of systemic estrogen with/without progestin) and both PF10 and the 36-Item Short-Form Health Survey Physical Component Scale. We used a linear regression model adjusting for age, MS duration,

SUBMITTER: Bove R 

PROVIDER: S-EPMC5075979 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature