The Effect of Diurnal Fluctuation in Intraocular Pressure on the Evaluation of Risk Factors of Progression in Normal Tension Glaucoma.

ABSTRACT:

Purpose

To investigate whether diurnal fluctuation in intraocular pressure (IOP) can influence the result of the correlations between IOP-related factors and progression of normal tension glaucoma (NTG).

Methods

Glaucoma progression was defined as visual field (VF) progression and changes in the optic disc and/or retinal nerve fiber layer (RNFL). Two different methods were used to evaluate the impact of the diurnal fluctuation in IOP. 'Conventional method' used in previous studies included all IOP measurements during the follow up time. 'Time adjusted method' was used to adjust diurnal fluctuation in IOP with the preferred time. Mean IOP, long term IOP fluctuation and the difference between the lowest and highest IOP were calculated using both methods. Cox regression analyse

SUBMITTER: Kim SH 

PROVIDER: S-EPMC5077094 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature