Ontology highlight
ABSTRACT:
SUBMITTER: von Massenhausen A
PROVIDER: S-EPMC5078043 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Oncotarget 20160501 22
Although head and neck cancer (HNSCC) is the sixth most common tumor entity worldwide therapy options remain limited leading to 5-year survival rates of only 50 %. MERTK is a promising therapeutic target in several tumor entities, however, its role in HNSCC has not been described yet. The aim of our study was to investigate the biological significance of MERTK and to evaluate its potential as a novel therapeutic target in this dismal tumor entity. In two large HNSCC cohorts (n=537 and n=520) we ...[more]