Clinical significance of serum omentin-1 levels in patients with pancreatic adenocarcinoma.

ABSTRACT:

Background

Omentin is related with metabolic syndrome and obesity. Pancreatic adenocarcinoma (PA) is a lethal and obesity-linked malignancy. This study was conducted to investigate the serum levels of omentin in patients with PA and the relationship with tumor progression and known prognostic parameters.

Material and methods

Serum samples were obtained from thirty-three patients on first admission before any treatment. Age, sex and body mass index (BMI) matched 30 healthy controls were included in the analysis. Both serum omentin levels were measured using enzyme-linked immunosorbent assay (ELISA).

Results

The median age at diagnosis was 59 years (32-84 years). Twenty (61%) patients were men and the remaining were women. The most common metastatic site was liver in 23

SUBMITTER: Karabulut S 

PROVIDER: S-EPMC5079241 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature