A Comprehensive Analysis on the Association between Tobacco-Free Betel Quid and Risk of Head and Neck Cancer in Taiwanese Men.

ABSTRACT:

Objectives

Although betel quid (BQ) is an established risk factor of head and neck cancer (HNC), insufficiencies exist in the literature regarding the dose-response, BQ types, HNC sites, and BQ cessation. The current study was conducted to fill these insufficiencies.

Materials and methods

A hospital-based case-control study was conducted to evaluate the association between BQ and HNC. In-person interview was conducted to collect data on BQ chewing. The current analysis included 487 men newly diagnosed with HNC and 617 male controls who were frequency-matched to the cases by age. The association between BQ and HNC was assessed using multivariable unconditional logistic regression.

Results

Ever BQ chewing was associated with an increased HNC risk regardless of the BQ ty

SUBMITTER: Wu YH 

PROVIDER: S-EPMC5079549 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature