Molecular genetic approaches to understanding the comorbidity of psychiatric disorders.

ABSTRACT: Epidemiologic studies demonstrating high rates of co-occurrence among psychiatric disorders at the population level have contributed to large literatures focused on identifying the causal mechanisms underlying the patterns of co-occurrence among these disorders. Such efforts have long represented a core focus of developmental psychopathologists and have more recently been supported by the Research Domain Criteria initiative developed by the NIMH, which provides a further framework for how the hypothesized mechanisms can be studied at different levels of analysis. The present overview focuses on molecular genetic approaches that are being used currently to study the etiology of psychiatric disorders, and how these approaches have been applied in efforts to understand the biological mechanis

SUBMITTER: Gizer IR 

PROVIDER: S-EPMC5079621 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature