Spatial pattern of genetic diversity and selection in the MHC class II DRB of three Neotropical bat species.

ABSTRACT:

Background

Although bats are natural reservoirs of many pathogens, few studies have been conducted on the genetic variation and detection of selection in major histocompatibility complex (MHC) genes. These genes are critical for resistance and susceptibility to diseases, and host-pathogen interactions are major determinants of their extensive polymorphism. Here we examined spatial patterns of diversity of the expressed MHC class II DRB gene of three sympatric Neotropical bats, Carollia perspicillata and Desmodus rotundus (Phyllostomidae), and Molossus molossus (Molossidae), all of which use the same environments (e.g., forests, edge habitats, urban areas). Comparison with neutral marker (mtDNA D-loop) diversity was performed at the same time.

Results

Twenty-three DRB alleles

SUBMITTER: Salmier A 

PROVIDER: S-EPMC5080761 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature