Ontology highlight
ABSTRACT:
SUBMITTER: Harbi S
PROVIDER: S-EPMC5081534 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Harbi Shaghayegh S Wang Rong R Gregory Michael M Hanson Nicole N Kobylarz Keith K Ryan Kamilah K Deng Yan Y Lopez Peter P Chiriboga Luis L Mignatti Paolo P
Scientific reports 20161027
Infantile hemangioma (IH) is the most common tumor of infancy. Its cellular origin and biological signals for uncontrolled growth are poorly understood, and specific pharmacological treatment is unavailable. To understand the process of hemangioma-genesis we characterized the progenitor hemangioma-derived stem cell (HemSC) and its lineage and non-lineage derivatives. For this purpose we performed a high-throughput (HT) phenotypic and gene expression analysis of HemSCs, and analyzed HemSC-derived ...[more]