Allelic barley MLA immune receptors recognize sequence-unrelated avirulence effectors of the powdery mildew pathogen.

ABSTRACT: Disease-resistance genes encoding intracellular nucleotide-binding domain and leucine-rich repeat proteins (NLRs) are key components of the plant innate immune system and typically detect the presence of isolate-specific avirulence (AVR) effectors from pathogens. NLR genes define the fastest-evolving gene family of flowering plants and are often arranged in gene clusters containing multiple paralogs, contributing to copy number and allele-specific NLR variation within a host species. Barley mildew resistance locus a (Mla) has been subject to extensive functional diversification, resulting in allelic resistance specificities each recognizing a cognate, but largely unidentified, AVR_a gene of the powdery mildew fungus, Blumeria graminis f. sp. hordei (Bgh). We applied a transcripto

SUBMITTER: Lu X 

PROVIDER: S-EPMC5081590 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature