Lifespan adversity and later adulthood telomere length in the nationally representative US Health and Retirement Study.

ABSTRACT: Stress over the lifespan is thought to promote accelerated aging and early disease. Telomere length is a marker of cell aging that appears to be one mediator of this relationship. Telomere length is associated with early adversity and with chronic stressors in adulthood in many studies. Although cumulative lifespan adversity should have bigger impacts than single events, it is also possible that adversity in childhood has larger effects on later life health than adult stressors, as suggested by models of biological embedding in early life. No studies have examined the individual vs. cumulative effects of childhood and adulthood adversities on adult telomere length. Here, we examined the relationship between cumulative childhood and adulthood adversity, adding up a range of severe financial

SUBMITTER: Puterman E 

PROVIDER: S-EPMC5081642 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature