Novel Immunotherapeutic Approaches for Head and Neck Squamous Cell Carcinoma.

ABSTRACT: The immune system plays a key role in preventing tumor formation by recognizing and destroying malignant cells. For over a century, researchers have attempted to harness the immune response as a cancer treatment, although this approach has only recently achieved clinical success. Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and is associated with cigarette smoking, alcohol consumption, betel nut use, and human papillomavirus infection. Unfortunately, worldwide mortality from HNSCC remains high, partially due to limits on therapy secondary to the significant morbidity associated with current treatments. Therefore, immunotherapeutic approaches to HNSCC treatment are attractive for their potential to reduce morbidity while improving survival. However

SUBMITTER: Bann DV 

PROVIDER: S-EPMC5082377 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature