Patterns of Nonrandom Mating Within and Across 11 Major Psychiatric Disorders.

ABSTRACT:

Importance

Psychiatric disorders are heritable, polygenic traits, which often share risk alleles and for which nonrandom mating has been suggested. However, despite the potential etiological implications, the scale of nonrandom mating within and across major psychiatric conditions remains unclear.

Objective

To quantify the nature and extent of nonrandom mating within and across a broad range of psychiatric conditions at the population level.

Design, setting, and participants

Population-based cohort using Swedish population registers. Participants were all Swedish residents with a psychiatric diagnosis of interest (attention-deficit/hyperactivity disorder, autism spectrum disorder, schizophrenia, bipolar disorder, major depression, generalized anxiety disorder, agoraph

SUBMITTER: Nordsletten AE 

PROVIDER: S-EPMC5082975 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature